Oncology

Chemotherapy: What to Actually Expect

Medically reviewed by Dr. Rajdeep Gupta, Medical Oncologist, M.D., D.N.B. Medical Oncology · Updated July 13, 2026
Chemotherapy uses drugs to kill or slow cancer cells throughout the body. It is usually given in cycles — treatment followed by a recovery period — over weeks or months. Side effects like fatigue, nausea and low immunity are common but increasingly well managed. Most people continue important parts of daily life during treatment.

How Chemotherapy Works

Unlike surgery or radiation, which treat one area, chemotherapy circulates through the body, making it valuable when cancer may have spread or to shrink a tumour before other treatment. It targets rapidly dividing cells — which is why it affects cancer, but also causes side effects in fast-growing normal cells like hair and the gut lining. It is usually given in cycles: a dose, then a recovery gap that lets healthy cells recover before the next.

What Treatment Day Is Like

Chemotherapy is often given as an infusion through a vein, sometimes as tablets. Infusion sessions can take from under an hour to several hours depending on the regimen, usually in a day-care setting where patients can sit comfortably. Many people bring something to read or a companion. Your team monitors you and manages any immediate reactions.

Managing Side Effects

Side effects vary by drug and person. Common ones — fatigue, nausea, hair thinning, and a temporarily weakened immune system — are anticipated and managed with supportive medication. Anti-nausea drugs today are very effective; infection precautions protect against low immunity. Telling your team promptly about any new symptom is important, particularly fever, which needs urgent attention during chemotherapy.

Living Through Treatment

Many people work, spend time with family and maintain much of their routine during chemotherapy, adjusting around lower-energy days. Good nutrition, rest, gentle activity and emotional support all help. Cancer treatment is a marathon, and looking after wellbeing through it is part of the treatment, not separate from it.

Common Questions

Does chemotherapy always cause hair loss?

No — hair loss depends on the specific drugs used. Some cause significant hair loss, others little or none. Your oncology team can tell you what to expect from your particular regimen.

Can I work during chemotherapy?

Many people continue working, at least part-time, adjusting around lower-energy days and treatment sessions. It depends on the regimen, your job and how you feel. Your team can advise on what is realistic.

What should prompt an urgent call during chemotherapy?

Fever, signs of infection, uncontrolled vomiting, or unusual bleeding need urgent attention during chemotherapy, because treatment can lower immunity and blood counts. Your team will give you clear guidance on when to call.

Questions About Chemotherapy? Talk to Our Oncology Team

Book a consultation with a Health1 specialist — online, by phone on 079 6999 6999, or on WhatsApp. For emergencies, call 90331 14444 (24×7).

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